CTSK

Across TCGA patient cohorts, CTSK protein abundance is significantly associated with the RNA expression of many other genes, with 9,938 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CTSK-associated genes across cancer lineages are CCN4, EFEMP2, and ASPN. Each is linked with CTSK in more than 8 cancer types. Because this analysis shows association rather than direction, both CTSK-to-partner and partner-to-CTSK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSK versus CCN4 in GBM, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSK→partner) and Y-score (partner→CTSK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CCN4 →	+2.051	+1.376	.001	.002	3	9
OV	EFEMP2 →	+1.263	+1.501	<.001	<.001	3	9
OV	ASPN →	+2.656	+1.200	<.001	<.001	3	8
OV	DCN →	+2.017	+1.404	<.001	<.001	3	8
UCEC	SGIP1 →	+1.197	+0.604	<.001	<.001	3	8
OV	TGFB3 →	+1.506	+1.114	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,938 associations by consensus.

CTSK vs CCN4 — GBM

Explore this scatter interactively →