CTSK

Across TCGA cell cohorts, CTSK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,313 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CTSK-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Macroautophagy. Each is linked with CTSK in more than 11 cancer types. Because this analysis shows association rather than direction, both CTSK-to-partner and partner-to-CTSK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by CTSK-low versus CTSK-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSK→partner) and Y-score (partner→CTSK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Process utilizing autophagic mechanism →	+0.057	+1.388	<.001	<.001	3	12
LIVER	Autophagy →	+0.057	+1.388	<.001	<.001	3	12
OESOPHAGUS	Macroautophagy →	+0.077	+0.938	<.001	<.001	3	12
SKIN	Cytosolic transport →	+0.065	+3.118	<.001	<.001	3	11
PANCREAS	Regulation of macroautophagy →	+0.054	+0.918	.002	<.001	3	11
OVARY	Regulation of TORC1 signaling →	+0.041	+0.954	.009	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,313 associations by consensus.

Process utilizing autophagic mechanism by CTSK expression — LIVER

Explore this box plot interactively →