CTSG

Across TCGA patient cohorts, CTSG RNA expression is significantly associated with the protein abundance of many other proteins, with 16,870 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CTSG-associated proteins across cancer lineages are CMA1, CPA3, and CAVIN2. Each is linked with CTSG in more than 8 cancer types. Because this analysis shows association rather than direction, both CTSG-to-partner and partner-to-CTSG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSG versus CMA1 in OV, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSG→partner) and Y-score (partner→CTSG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CMA1 →	+1.120	+0.752	<.001	<.001	3	9
BRCA	CPA3 →	+1.283	+1.654	<.001	<.001	3	9
BRCA	CAVIN2 →	+0.996	+1.357	<.001	<.001	3	8
BRCA	COL14A1 →	+0.924	+1.250	<.001	<.001	3	8
OV	NOP56_S520 →	-1.137	-0.881	<.001	<.001	3	8
OV	SNRNP70_S226 →	-0.464	-0.607	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,870 associations by consensus.

CTSG vs CMA1 — OV

Explore this scatter interactively →