CTSG

Across TCGA cell cohorts, CTSG protein abundance is significantly associated with the RNA expression of many other genes, with 1,506 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CTSG-associated genes across cancer lineages are ZC4H2, KRT18, and C9orf50. Each is linked with CTSG in more than 3 cancer types. Because this analysis shows association rather than direction, both CTSG-to-partner and partner-to-CTSG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSG versus ZC4H2 in LIVER, with a Pearson correlation of -0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSG→partner) and Y-score (partner→CTSG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	ZC4H2 →	-3.034	-2.692	.001	<.001	3	4
LARGE_INTESTINE	KRT18 →	+1.894	+2.192	<.001	<.001	3	4
LARGE_INTESTINE	C9orf50 →	+0.040	+1.152	.003	.005	3	4
LIVER	LYNX1 →	-1.485	-2.692	.005	<.001	3	3
LIVER	RTL6 →	-3.573	-3.319	<.001	.003	3	3
PANCREAS	ELOVL7 →	+2.050	+1.221	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,506 associations by consensus.

CTSG vs ZC4H2 — LIVER

Explore this scatter interactively →