CTSF

Across TCGA patient cohorts, CTSF RNA expression is significantly associated with the protein abundance of many other proteins, with 15,645 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CTSF-associated proteins across cancer lineages are HDGFL3, SSC5D, and TLN2. Each is linked with CTSF in more than 6 cancer types. Because this analysis shows association rather than direction, both CTSF-to-partner and partner-to-CTSF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSF versus HDGFL3 in BRCA, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSF→partner) and Y-score (partner→CTSF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL3 →	+0.642	+0.750	<.001	<.001	3	7
PDAC	SSC5D →	+0.801	+0.659	<.001	<.001	3	6
HNSC	TLN2 →	+0.504	+0.651	<.001	.004	3	6
LUAD	UTRN →	+0.225	+0.508	.001	.005	3	6
BRCA	NOP2_S732 →	-0.614	-0.676	<.001	<.001	3	6
HNSC	PEBP1 →	+0.342	+0.691	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,645 associations by consensus.

CTSF vs HDGFL3 — BRCA

Explore this scatter interactively →