CTSF

Across TCGA patient cohorts, CTSF protein abundance is significantly associated with the RNA expression of many other genes, with 10,816 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CTSF-associated genes across cancer lineages are CBX7, CKS2, and APBB1. Each is linked with CTSF in more than 6 cancer types. Because this analysis shows association rather than direction, both CTSF-to-partner and partner-to-CTSF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSF versus CBX7 in OV, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSF→partner) and Y-score (partner→CTSF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CBX7 →	+0.987	+0.795	<.001	.004	2	7
BRCA	CKS2 →	-0.974	-0.645	<.001	<.001	3	6
UCEC	APBB1 →	+0.842	+0.544	.003	.001	3	6
UCEC	NEGR1 →	+0.777	+0.583	<.001	<.001	3	6
HNSC	PRELP →	+1.318	+0.605	<.001	<.001	3	6
BRCA	ORC1 →	-0.954	-0.571	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,816 associations by consensus.

CTSF vs CBX7 — OV

Explore this scatter interactively →