Across TCGA patient cohorts, CTSE RNA expression is significantly associated with the protein abundance of many other proteins, with 12,407 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CTSE-associated proteins across cancer lineages are NOSTRIN, PMS2_S445, and LRPPRC. Each is linked with CTSE in more than 4 cancer types. Because this analysis shows association rather than direction, both CTSE-to-partner and partner-to-CTSE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSE→partner) and Y-score (partner→CTSE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NOSTRIN →	+0.444	+2.147	<.001	<.001	3	5
BRCA	PMS2_S445 →	-0.792	-0.454	.001	.008	3	5
COAD	LRPPRC →	-0.435	-2.033	<.001	<.001	3	4
UCEC	MRPS5 →	-0.307	-1.211	.004	.002	3	4
COAD	NHP2 →	-0.387	-2.733	<.001	<.001	3	4
BRCA	PAPSS2 →	+0.521	+0.721	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,407 associations by consensus.

Exploration

CTSE survival (RNA) · tumor vs normal (RNA) · all CTSE data types