CTRB2

Across TCGA cell cohorts, CTRB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,812 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CTRB2-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Establishment of protein localization to membrane, and Negative regulation of myoblast fusion. Each is linked with CTRB2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CTRB2-to-partner and partner-to-CTRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by CTRB2-low versus CTRB2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTRB2→partner) and Y-score (partner→CTRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.108	+0.142	<.001	.002	3	9
PANCREAS	Establishment of protein localization to membrane →	+0.056	+0.158	<.001	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.122	+0.110	<.001	.004	3	8
BREAST	Response to starvation →	+0.036	+0.093	.001	.002	2	9
BREAST	Regulation of RNA splicing →	+0.072	+0.118	<.001	<.001	3	8
BREAST	Regulation of mRNA processing →	+0.092	+0.113	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,812 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by CTRB2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →