CTRB1

Across TCGA cell cohorts, CTRB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,113 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CTRB1-associated GO terms across cancer lineages are Regulation of protein localization to nucleus, Regulation of mRNA processing, and Regulation of nucleocytoplasmic transport. Each is linked with CTRB1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CTRB1-to-partner and partner-to-CTRB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to nucleus grouped by CTRB1-low versus CTRB1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTRB1→partner) and Y-score (partner→CTRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of protein localization to nucleus →	+0.043	+0.124	<.001	.002	3	10
BREAST	Regulation of mRNA processing →	+0.086	+0.104	<.001	<.001	3	10
BREAST	Regulation of nucleocytoplasmic transport →	+0.063	+0.151	<.001	.008	2	10
CNS	mRNA transport →	+0.043	+0.091	<.001	.004	3	9
BREAST	Protein stabilization →	+0.064	+0.155	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Protein-containing complex disassembly →	+0.070	+0.085	.001	.002	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,113 associations by consensus.

Regulation of protein localization to nucleus by CTRB1 expression — LARGE_INTESTINE

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