CTPS2

Across TCGA cell cohorts, CTPS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,496 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CTPS2-associated GO terms across cancer lineages are Copper ion export, Glycerophospholipid metabolic process, and Post-Golgi vesicle-mediated transport. Each is linked with CTPS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CTPS2-to-partner and partner-to-CTPS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by CTPS2-low versus CTPS2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTPS2→partner) and Y-score (partner→CTPS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Copper ion export →	-0.174	-0.928	.001	<.001	3	8
BREAST	Glycerophospholipid metabolic process →	+0.045	+1.433	<.001	<.001	3	8
LUNG_SCLC	Post-Golgi vesicle-mediated transport →	+0.069	+1.082	<.001	<.001	3	8
BREAST	Negative regulation of T-helper cell differentiation →	-0.129	-1.201	<.001	.001	2	8
BREAST	Regulation of T-helper 1 cell differentiation →	-0.557	-0.685	.006	.008	3	7
BREAST	Base-excision repair, gap-filling →	+0.118	+1.049	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,496 associations by consensus.

Copper ion export by CTPS2 expression — OVARY

Explore this box plot interactively →