CTPS1

Across TCGA patient cohorts, CTPS1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,810 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CTPS1-associated genes across cancer lineages are CDC20, CENPI, and CENPA. Each is linked with CTPS1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CTPS1-to-partner and partner-to-CTPS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTPS1 versus CDC20 in LUAD, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTPS1→partner) and Y-score (partner→CTPS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDC20 →	+1.789	+0.321	<.001	<.001	3	10
UCEC	CENPI →	+0.986	+0.336	<.001	<.001	3	9
LUAD	CENPA →	+1.356	+0.253	<.001	<.001	3	9
LUAD	DLGAP5 →	+1.701	+0.293	<.001	<.001	3	9
BRCA	CDCA8 →	+1.203	+0.534	<.001	<.001	3	9
LUAD	KIF2C →	+1.484	+0.319	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,810 associations by consensus.

CTPS1 vs CDC20 — LUAD

Explore this scatter interactively →