CTNS

Across TCGA patient cohorts, CTNS protein abundance is significantly associated with the RNA expression of many other genes, with 12,789 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CTNS-associated genes across cancer lineages are FAM241A, KLF12, and ATAT1. Each is linked with CTNS in more than 6 cancer types. Because this analysis shows association rather than direction, both CTNS-to-partner and partner-to-CTNS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTNS versus FAM241A in BRCA, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNS→partner) and Y-score (partner→CTNS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM241A →	+0.994	+0.757	<.001	<.001	3	7
HNSC	KLF12 →	-0.701	-0.474	.003	.002	3	4
HNSC	ATAT1 →	-0.580	-0.322	<.001	.003	3	4
HNSC	ZNF496 →	-0.522	-0.481	.002	.002	3	4
GBM	TUB →	-0.741	-0.677	.001	.005	3	4
HNSC	GPR39 →	+0.948	+0.365	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,789 associations by consensus.

CTNS vs FAM241A — BRCA

Explore this scatter interactively →