Across TCGA patient cohorts, CTNND1 mutation is significantly associated with the RNA expression of many other genes, with 2,925 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTNND1-associated genes across cancer lineages are UHRF1, RPL22P14, and MTND5P17. Each is linked with CTNND1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CTNND1-to-partner and partner-to-CTNND1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNND1→partner) and Y-score (partner→CTNND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UHRF1 →	+0.615	+1.949	<.001	<.001	3	3
LUAD	RPL22P14 →	+0.093	+3.376	.001	.008	3	3
HNSC	MTND5P17 →	+0.028	+4.736	<.001	.007	3	3
KIRC	SYF2P1 →	+0.242	+4.895	<.001	.005	3	3
UCEC	ATG4A →	+0.339	+1.440	<.001	<.001	3	3
UCEC	GLA →	+0.353	+1.686	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,925 associations by consensus.

Exploration

CTNND1 survival (RNA) · tumor vs normal (RNA) · all CTNND1 data types