Across TCGA patient cohorts, CTNND1 mutation is significantly associated with the total protein of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTNND1-associated genes across cancer lineages are PCNA, Src_pY527, and Caspase-7-cleavedD198. Each is linked with CTNND1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CTNND1-to-partner and partner-to-CTNND1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNND1→partner) and Y-score (partner→CTNND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.174	+1.584	.003	<.001	3	3
UCEC	Src_pY527 →	-0.242	-0.951	.039	.037	3	3
UCEC	Caspase-7-cleavedD198 →	+0.502	+1.736	.001	.001	3	3
COAD	C-Raf →	+0.205	+3.467	.001	.002	3	3
COAD	EGFR_pY1173 →	+0.095	+2.364	.027	.018	3	3
STAD	RBM15 →	+0.455	+3.000	.047	.036	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

Exploration

CTNND1 survival (RNA) · tumor vs normal (RNA) · all CTNND1 data types