CTNNBL1

Across TCGA pan-cancer cohorts, CTNNBL1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CTNNBL1 data layer compared with 27 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CTNNBL1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CTNNBL1 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

COAD, LUAD, and OV are the cancer types where CTNNBL1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.101	0.673	<.001	27	view →
LUAD	OS	Median	II,III,IV	0.111	0.750	<.001	24	view →
OV	OS	Median	IV	0.028	0.759	.002	12	view →
LIHC	OS	Median	III,IV	0.270	0.732	.021	9	view →
SKCM	OS	Median	All	1.000	0.868	.046	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CTNNBL1–COAD (OS)

Open the COAD breakdown →