CTNNBL1

Across TCGA pan-cancer cohorts, CTNNBL1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CTNNBL1 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CTNNBL1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CTNNBL1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, PDAC, and HNSC are the cancer types where CTNNBL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.839	0.574	<.001	44	view →
PDAC	OS	Quartile	All	0.315	0.709	<.001	34	view →
HNSC	OS	Quartile	All	0.140	1.000	.017	28	view →
CCRCC	DFS	Tertile	All	0.855	0.974	.004	18	view →
OV	DFS	Median	All	0.876	1.000	.046	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CTNNBL1–LSCC (DFS)

Open the LSCC breakdown →