CTNNBIP1

Across TCGA patient cohorts, CTNNBIP1 mutation is significantly associated with the RNA expression of many other genes, with 219 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTNNBIP1-associated genes across cancer lineages are UBFD1P1, RNU7-173P, and CCT3P1. Each is linked with CTNNBIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTNNBIP1-to-partner and partner-to-CTNNBIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBFD1P1 grouped by CTNNBIP1-low versus CTNNBIP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNNBIP1→partner) and Y-score (partner→CTNNBIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	UBFD1P1 →	+0.104	+6.721	.008	<.001	3	2
CESC	RNU7-173P →	+0.610	+5.969	<.001	.002	3	2
SKCM	CCT3P1 →	+0.086	+5.097	<.001	.008	3	2
COAD	RNA5SP90 →	+1.016	+5.017	<.001	.009	3	1
COAD	RPS26P30 →	+0.222	+5.283	.006	.006	3	1
COAD	CD24P1 →	+0.443	+5.357	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 219 associations by consensus.

UBFD1P1 by CTNNBIP1 expression — COAD

Explore this box plot interactively →