CTNNB1

Across TCGA patient cohorts, CTNNB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,426 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CTNNB1-associated proteins across cancer lineages are NT5DC2, SPCS3, and CD38. Each is linked with CTNNB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CTNNB1-to-partner and partner-to-CTNNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTNNB1 versus NT5DC2 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNNB1→partner) and Y-score (partner→CTNNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NT5DC2 →	+0.450	+0.377	<.001	<.001	3	5
LSCC	SPCS3 →	-0.542	-0.385	<.001	<.001	3	5
CCRCC	CD38 →	-0.755	-0.357	.001	.006	3	5
OV	VCL_Y822 →	+1.490	+1.131	.001	<.001	3	5
GBM	SVIL →	+0.524	+0.375	<.001	<.001	3	5
BRCA	RPL6 →	-0.562	-0.656	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,426 associations by consensus.

CTNNB1 vs NT5DC2 — LSCC

Explore this scatter interactively →