CTNNB1

Across TCGA patient cohorts, CTNNB1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,551 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CTNNB1-associated genes across cancer lineages are CCR5, TFEC, and CD72. Each is linked with CTNNB1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CTNNB1-to-partner and partner-to-CTNNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTNNB1 versus CCR5 in COAD, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNNB1→partner) and Y-score (partner→CTNNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CCR5 →	-1.042	-0.413	<.001	<.001	3	8
OV	TFEC →	-0.803	-0.279	<.001	<.001	3	7
OV	CD72 →	-1.201	-0.351	<.001	.006	3	7
OV	CYTH4 →	-1.078	-0.360	<.001	.008	3	7
OV	SLA2 →	-1.042	-0.406	<.001	.002	3	7
OV	TLR8 →	-1.244	-0.331	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,551 associations by consensus.

CTNNB1 vs CCR5 — COAD

Explore this scatter interactively →