CTNNA1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CTNNA1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,991 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CTNNA1-associated genes across cancer lineages are PLEK, SRGN, and GMFG. Each is linked with CTNNA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CTNNA1-to-partner and partner-to-CTNNA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTNNA1 versus PLEK in HNSC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNNA1→partner) and Y-score (partner→CTNNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCPLEK →-1.266-0.292<.001.00139
HNSCSRGN →-1.392-0.411<.001<.00139
OVGMFG →-1.171-0.437<.001<.00139
OVDOCK2 →-1.006-0.488<.001.00139
HNSCMYO1F →-1.003-0.436<.001<.00139
HNSCCD53 →-1.416-0.427<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,991 associations by consensus.

CTNNA1 vs PLEK — HNSC

Per-sample scatter of CTNNA1 vs PLEK in HNSC (Pearson r = -0.28).

Explore this scatter interactively →

Exploration