CTNNA1

Across TCGA cell cohorts, CTNNA1 mutation is significantly associated with the RNA expression of many other genes, with 1,002 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CTNNA1-associated genes across cancer lineages are IL1F10, KRT72, and OR5M8. Each is linked with CTNNA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTNNA1-to-partner and partner-to-CTNNA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL1F10 grouped by CTNNA1-low versus CTNNA1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNNA1→partner) and Y-score (partner→CTNNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	IL1F10 →	+0.220	+4.643	<.001	.003	3	1
CNS	KRT72 →	+0.270	+5.044	<.001	.001	3	1
CNS	OR5M8 →	+0.017	+4.754	<.001	.005	3	1
CNS	SPATA31A6 →	+0.109	+4.169	<.001	.008	3	1
CNS	KRT73 →	+0.102	+5.044	<.001	.001	3	1
CNS	KRTAP19-2 →	+0.074	+4.754	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,002 associations by consensus.

IL1F10 by CTNNA1 expression — CNS

Explore this box plot interactively →