CTIF

Across TCGA patient cohorts, CTIF RNA expression is significantly associated with the protein abundance of many other proteins, with 18,143 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CTIF-associated proteins across cancer lineages are EFEMP2, MMP2, and ISLR. Each is linked with CTIF in more than 7 cancer types. Because this analysis shows association rather than direction, both CTIF-to-partner and partner-to-CTIF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTIF versus EFEMP2 in CCRCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTIF→partner) and Y-score (partner→CTIF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	EFEMP2 →	+0.657	+0.319	.002	<.001	3	8
OV	MMP2 →	+0.678	+0.643	<.001	<.001	3	8
OV	ISLR →	+0.739	+0.742	<.001	<.001	3	8
HNSC	MAP1A →	+0.502	+0.495	<.001	<.001	3	8
OV	CTHRC1 →	+0.802	+0.595	<.001	<.001	3	7
OV	FBLN1 →	+0.780	+0.683	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,143 associations by consensus.

CTIF vs EFEMP2 — CCRCC

Explore this scatter interactively →