CTIF

Across TCGA cell cohorts, CTIF RNA expression is significantly associated with the go_rna of many other GO terms, with 4,554 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CTIF-associated GO terms across cancer lineages are Calcium-independent cell-matrix adhesion, Retrograde transport, endosome to Golgi, and Cell division. Each is linked with CTIF in more than 11 cancer types. Because this analysis shows association rather than direction, both CTIF-to-partner and partner-to-CTIF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium-independent cell-matrix adhesion grouped by CTIF-low versus CTIF-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTIF→partner) and Y-score (partner→CTIF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Calcium-independent cell-matrix adhesion →	+0.238	+2.130	.001	<.001	3	12
OESOPHAGUS	Retrograde transport, endosome to Golgi →	+0.090	+1.286	<.001	<.001	3	11
BREAST	Cell division →	+0.067	+1.127	.001	<.001	3	11
BONE	Regulation of focal adhesion assembly →	+0.216	+1.858	<.001	<.001	3	10
BONE	Regulation of protein K48-linked ubiquitination →	+0.174	+1.521	<.001	<.001	3	10
BONE	Establishment of protein localization to plasma membrane →	+0.119	+1.567	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,554 associations by consensus.

Calcium-independent cell-matrix adhesion by CTIF expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →