CTHRC1P1

Across TCGA pan-cancer cohorts, CTHRC1P1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated CTHRC1P1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CTHRC1P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CTHRC1P1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LAML show a favorable association.

UVM, OV, and COAD are the cancer types where CTHRC1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	II,III,IV	0.281	0.777	.003	63	view →
OV	DFS	Tertile	IV	0.073	0.486	<.001	36	view →
COAD	OS	Tertile	IV	0.130	0.674	<.001	36	view →
KIRP	OS	Tertile	All	0.353	0.705	.004	18	view →
MESO	OS	Tertile	IV	0.384	0.634	.023	15	view →
SKCM	OS	Tertile	All	0.442	0.316	.005	12	view →
LAML	DFS	Quartile	All	0.624	0.285	.031	6	view →
THYM	OS	Median	II,III,IV	1.000	0.686	.030	3	view →
LUSC	DFS	Tertile	III,IV	1.000	0.270	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

CTHRC1P1–UVM (DFS)

Open the UVM breakdown →