CTHRC1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CTHRC1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,858 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CTHRC1-associated genes across cancer lineages are RUNX2, LOXL2, and LRRC15. Each is linked with CTHRC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CTHRC1-to-partner and partner-to-CTHRC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTHRC1 versus RUNX2 in OV, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTHRC1→partner) and Y-score (partner→CTHRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRUNX2 →+1.280+1.056<.001<.001310
OVLOXL2 →+1.285+1.231<.001<.001310
OVLRRC15 →+2.093+1.337<.001<.001310
OVMEDAG →+1.664+1.094<.001<.00139
OVPRRX1 →+2.336+1.318<.001<.00139
OVINHBA →+2.395+1.270<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,858 associations by consensus.

CTHRC1 vs RUNX2 — OV

Per-sample scatter of CTHRC1 vs RUNX2 in OV (Pearson r = 0.63).

Explore this scatter interactively →

Exploration