CTHRC1

Across TCGA patient cohorts, CTHRC1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTHRC1-associated genes across cancer lineages are ACC1 and STAT3_pY705. Each is linked with CTHRC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTHRC1-to-partner and partner-to-CTHRC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by CTHRC1-low versus CTHRC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTHRC1→partner) and Y-score (partner→CTHRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.529	+3.169	.008	.020	3	1
UCEC	STAT3_pY705 →	-0.397	-3.169	.005	.020	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ACC1 by CTHRC1 expression — UCEC

Explore this box plot interactively →