CTHRC1

Across TCGA cell cohorts, CTHRC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,695 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CTHRC1-associated GO terms across cancer lineages are Regulation of intracellular transport, Positive regulation of intracellular transport, and Regulation of intracellular protein transport. Each is linked with CTHRC1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CTHRC1-to-partner and partner-to-CTHRC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular transport grouped by CTHRC1-low versus CTHRC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTHRC1→partner) and Y-score (partner→CTHRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of intracellular transport →	+0.062	+3.006	<.001	.001	2	12
BONE	Positive regulation of intracellular transport →	+0.079	+3.130	<.001	.003	3	11
URINARY_TRACT	Regulation of intracellular protein transport →	+0.088	+2.450	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Positive regulation of intracellular protein transport →	+0.055	+3.307	<.001	<.001	3	11
OESOPHAGUS	Response to hypoxia →	+0.077	+2.786	<.001	<.001	3	10
OESOPHAGUS	Regulation of protein modification by small protein conjugation or removal →	+0.068	+3.049	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,695 associations by consensus.

Regulation of intracellular transport by CTHRC1 expression — BONE

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