CTH

Across TCGA patient cohorts, CTH RNA expression is significantly associated with the RNA expression of many other genes, with 18,929 significant associations in total. THYM shows the largest number of these associations.

The most reproducible CTH-associated genes across cancer lineages are NARS2, SLC35A3, and ANKRD13C. Each is linked with CTH in more than 31 cancer types. Because this analysis shows association rather than direction, both CTH-to-partner and partner-to-CTH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTH versus NARS2 in DLBC, with a Pearson correlation of 0.63.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTH→partner) and Y-score (partner→CTH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	NARS2 →	+1.145	+1.854	<.001	<.001	3	32
THYM	SLC35A3 →	+0.944	+0.659	<.001	<.001	3	31
UVM	ANKRD13C →	+0.964	+0.813	<.001	<.001	3	30
DLBC	PPAT →	+1.058	+1.500	<.001	<.001	3	30
TGCT	PDIA6 →	+1.454	+0.963	<.001	<.001	3	30
UVM	AHCYL1 →	+1.048	+0.885	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,929 associations by consensus.

CTH vs NARS2 — DLBC

Explore this scatter interactively →