CTH

Across TCGA patient cohorts, CTH RNA expression is significantly associated with the protein abundance of many other proteins, with 8,722 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CTH-associated proteins across cancer lineages are DFFA, NFIA, and ZNF385A_S160. Each is linked with CTH in more than 3 cancer types. Because this analysis shows association rather than direction, both CTH-to-partner and partner-to-CTH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTH versus DFFA in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTH→partner) and Y-score (partner→CTH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DFFA →	+0.298	+0.741	<.001	<.001	3	4
BRCA	NFIA →	+0.383	+0.549	<.001	<.001	3	3
CCRCC	ZNF385A_S160 →	-0.560	-0.450	.001	.002	3	3
GBM	SERPINF1 →	-0.672	-0.775	<.001	<.001	3	3
GBM	SPATA6_S217 →	+0.647	+0.526	<.001	<.001	3	3
GBM	THEMIS2_T593 →	-0.702	-0.786	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,722 associations by consensus.

CTH vs DFFA — GBM

Explore this scatter interactively →