CTH

Across TCGA patient cohorts, CTH protein abundance is significantly associated with the RNA expression of many other genes, with 16,944 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CTH-associated genes across cancer lineages are TUBA1B, GCAT, and GINS2. Each is linked with CTH in more than 4 cancer types. Because this analysis shows association rather than direction, both CTH-to-partner and partner-to-CTH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTH versus TUBA1B in HNSC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTH→partner) and Y-score (partner→CTH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TUBA1B →	-0.891	-0.405	.003	<.001	3	4
COAD	GCAT →	+0.649	+0.414	.001	.005	2	5
LSCC	GINS2 →	-0.867	-0.511	<.001	<.001	3	4
CCRCC	SFXN5 →	-0.452	-0.440	<.001	<.001	3	4
COAD	TSR2 →	-0.504	-0.449	<.001	.001	3	4
LSCC	CHCHD6 →	-0.724	-0.487	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,944 associations by consensus.

CTH vs TUBA1B — HNSC

Explore this scatter interactively →