CTF1

Across TCGA pan-cancer cohorts, CTF1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CTF1 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CTF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CTF1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where CTF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.856	0.626	.003	32	view →
HNSC	OS	Tertile	II,III,IV	1.000	0.825	.024	10	view →
LUAD	DFS	Tertile	II,III,IV	0.836	0.220	.030	8	view →
LSCC	OS	Median	All	0.937	1.000	.013	7	view →
UCEC	DFS	Median	III,IV	0.460	0.889	.044	4	view →
PDAC	DFS	Median	II,III,IV	0.277	0.786	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CTF1–CCRCC (DFS)

Open the CCRCC breakdown →