CTF1

Across TCGA patient cohorts, CTF1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,525 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CTF1-associated genes across cancer lineages are GINS1, EZH2, and KIF18A. Each is linked with CTF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CTF1-to-partner and partner-to-CTF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTF1 versus GINS1 in GBM, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTF1→partner) and Y-score (partner→CTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GINS1 →	-0.719	-0.364	<.001	<.001	3	3
GBM	EZH2 →	-0.697	-0.401	.001	<.001	3	3
OV	KIF18A →	-0.801	-0.455	<.001	<.001	3	3
GBM	PBK →	-1.009	-0.349	.003	.006	3	3
LUAD	HASPIN →	-0.737	-0.306	<.001	.002	3	3
BRCA	AURKA →	-0.870	-0.453	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,525 associations by consensus.

CTF1 vs GINS1 — GBM

Explore this scatter interactively →