CTF1

Across TCGA patient cohorts, CTF1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible CTF1-associated genes across cancer lineages are RNU4-79P, SNORD114-29, and RNU1-114P. Each is linked with CTF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTF1-to-partner and partner-to-CTF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-79P grouped by CTF1-low versus CTF1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTF1→partner) and Y-score (partner→CTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU4-79P →	+0.208	+7.640	<.001	.009	3	1
BLCA	SNORD114-29 →	+0.373	+7.640	<.001	.009	3	1
BLCA	RNU1-114P →	+0.179	+7.640	<.001	.009	3	1
BLCA	RNU6-187P →	+0.262	+7.640	<.001	.009	3	1
BLCA	MIR3938 →	+0.273	+7.640	<.001	.009	3	1
BLCA	RPL31P9 →	+0.268	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

RNU4-79P by CTF1 expression — BLCA

Explore this box plot interactively →