CTDSPL

Across TCGA patient cohorts, CTDSPL protein abundance is significantly associated with the RNA expression of many other genes, with 1,936 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CTDSPL-associated genes across cancer lineages are MIR4783, MTHFD2, and PRRT3. Each is linked with CTDSPL in more than 2 cancer types. Because this analysis shows association rather than direction, both CTDSPL-to-partner and partner-to-CTDSPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTDSPL versus MIR4783 in CCRCC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTDSPL→partner) and Y-score (partner→CTDSPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MIR4783 →	+0.667	+0.273	<.001	.005	3	2
LUAD	MTHFD2 →	-0.568	-0.327	.001	.001	3	2
BRCA	PRRT3 →	+2.054	+1.366	.003	.009	3	2
PDAC	XKRX →	+0.476	+0.406	<.001	<.001	3	2
BRCA	UNC13B →	+1.343	+1.291	.006	.007	3	2
HNSC	FAM228B →	+0.668	+0.361	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,936 associations by consensus.

CTDSPL vs MIR4783 — CCRCC

Explore this scatter interactively →