CTDSPL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CTDSPL protein abundance is significantly associated with the protein abundance of many other proteins, with 6,359 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CTDSPL-associated proteins across cancer lineages are CYP20A1, GPD1L, and CDC42SE2. Each is linked with CTDSPL in more than 2 cancer types. Because this analysis shows association rather than direction, both CTDSPL-to-partner and partner-to-CTDSPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTDSPL versus CYP20A1 in BRCA, with a Pearson correlation of 0.60.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTDSPL→partner) and Y-score (partner→CTDSPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACYP20A1 →+0.631+1.227.005.00333
PDACGPD1L →+0.446+0.497<.001<.00133
PDACCDC42SE2 →+0.661+0.617.008<.00132
BRCARPL23 →-0.600-1.137<.001.00232
BRCARPSA →-0.551-1.415<.001<.00132
BRCASRRM2_S1424 →+1.599+1.008<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,359 associations by consensus.

CTDSPL vs CYP20A1 — BRCA

Per-sample scatter of CTDSPL vs CYP20A1 in BRCA (Pearson r = 0.60).

Explore this scatter interactively →

Exploration