CTDSPL

Across TCGA cell cohorts, CTDSPL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,842 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CTDSPL-associated GO terms across cancer lineages are Regulation of G1/S transition of mitotic cell cycle, Negative regulation of actin filament polymerization, and Regulation of cell cycle G1/S phase transition. Each is linked with CTDSPL in more than 9 cancer types. Because this analysis shows association rather than direction, both CTDSPL-to-partner and partner-to-CTDSPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G1/S transition of mitotic cell cycle grouped by CTDSPL-low versus CTDSPL-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTDSPL→partner) and Y-score (partner→CTDSPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of G1/S transition of mitotic cell cycle →	+0.058	+1.709	<.001	<.001	3	10
URINARY_TRACT	Negative regulation of actin filament polymerization →	+0.178	+1.269	<.001	.003	3	8
BREAST	Regulation of cell cycle G1/S phase transition →	+0.037	+0.882	.009	<.001	3	8
BREAST	Positive regulation of cell cycle G1/S phase transition →	+0.072	+0.848	.002	<.001	3	8
LARGE_INTESTINE	Positive regulation of L-glutamate import across plasma membrane →	+0.039	+0.960	<.001	<.001	3	8
URINARY_TRACT	Regulation of actin filament depolymerization →	+0.126	+1.297	.007	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,842 associations by consensus.

Regulation of G1/S transition of mitotic cell cycle by CTDSPL expression — BLOOD_Leukemia

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