CTDSP2

Across TCGA patient cohorts, CTDSP2 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTDSP2-associated genes across cancer lineages are ATM, MEK1, and Notch1. Each is linked with CTDSP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTDSP2-to-partner and partner-to-CTDSP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by CTDSP2-low versus CTDSP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTDSP2→partner) and Y-score (partner→CTDSP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.537	-2.459	.014	.020	3	1
UCEC	MEK1 →	+0.484	+3.321	.006	.010	2	1
UCEC	Notch1 →	+0.209	+2.459	.002	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ATM by CTDSP2 expression — UCEC

Explore this box plot interactively →