CTDSP1

Across TCGA cell cohorts, CTDSP1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CTDSP1-associated genes across cancer lineages are TSHB, GPR101, and TPRX1. Each is linked with CTDSP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTDSP1-to-partner and partner-to-CTDSP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSHB grouped by CTDSP1-low versus CTDSP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTDSP1→partner) and Y-score (partner→CTDSP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TSHB →	+0.128	+4.276	.003	.007	3	1
BLOOD_Leukemia	GPR101 →	+0.167	+4.551	<.001	.004	3	1
BLOOD_Leukemia	TPRX1 →	+0.021	+5.060	<.001	.001	3	1
BLOOD_Leukemia	NKX2-6 →	+0.507	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	TMEM95 →	+0.028	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	NPAP1 →	+0.075	+4.551	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

TSHB by CTDSP1 expression — BLOOD_Leukemia

Explore this box plot interactively →