CTDNEP1

Across TCGA patient cohorts, CTDNEP1 mutation is significantly associated with the RNA expression of many other genes, with 116 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTDNEP1-associated genes across cancer lineages are RPS6P20, RNU6-492P, and RNU4-26P. Each is linked with CTDNEP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTDNEP1-to-partner and partner-to-CTDNEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS6P20 grouped by CTDNEP1-low versus CTDNEP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTDNEP1→partner) and Y-score (partner→CTDNEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS6P20 →	+0.137	+2.844	<.001	.002	3	2
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	1
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	1
UCEC	RPS29P32 →	+0.762	+3.014	<.001	.004	3	1
COAD	MTND3P1 →	+0.437	+4.602	<.001	.008	3	1
COAD	RPL35AP30 →	+0.438	+5.126	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 116 associations by consensus.

RPS6P20 by CTDNEP1 expression — UCEC

Explore this box plot interactively →