CTC1

Across TCGA patient cohorts, CTC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,086 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CTC1-associated proteins across cancer lineages are RPA1, NCOR1, and RRBP1_S615. Each is linked with CTC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CTC1-to-partner and partner-to-CTC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTC1 versus RPA1 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTC1→partner) and Y-score (partner→CTC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPA1 →	+0.276	+0.269	<.001	<.001	3	6
GBM	NCOR1 →	+0.313	+0.438	<.001	<.001	3	6
BRCA	RRBP1_S615 →	-0.710	-0.692	<.001	<.001	3	6
BRCA	SPAG7 →	+0.392	+0.770	<.001	<.001	3	5
LSCC	MYEF2 →	+0.814	+0.533	<.001	<.001	3	5
LSCC	NCBP3 →	+0.268	+0.461	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,086 associations by consensus.

CTC1 vs RPA1 — GBM

Explore this scatter interactively →