CTBS

RNA expression — cross-omics
Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CTBS RNA expression is significantly associated with the RNA expression of many other genes, with 20,022 significant associations in total. THYM shows the largest number of these associations.

The most reproducible CTBS-associated genes across cancer lineages are DPYD, TMEM167B, and FPGT. Each is linked with CTBS in more than 33 cancer types. Because this analysis shows association rather than direction, both CTBS-to-partner and partner-to-CTBS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTBS versus DPYD in CHOL, with a Pearson correlation of 0.73.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTBS→partner) and Y-score (partner→CTBS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CHOLDPYD →+2.086+1.476<.001<.001334
UVMTMEM167B →+1.279+1.363<.001<.001334
UVMFPGT →+1.447+1.402<.001<.001334
UVMPIGK →+1.514+1.463<.001<.001334
UVMMFSD14A →+1.609+1.485<.001<.001334
UVMSLC30A7 →+1.445+1.441<.001<.001334
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,022 associations by consensus.

CTBS vs DPYD — CHOL

Per-sample scatter of CTBS vs DPYD in CHOL (Pearson r = 0.73).

Explore this scatter interactively →

Exploration