Across TCGA pan-cancer cohorts, CTBP2P9 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of CTBP2P9’s most consistent transcriptional readouts.
The strongest signal is observed in esophageal carcinoma (ESCA), where CTBP2P9 RNA is repressed in tumor relative to normal tissue. In most cancer types CTBP2P9 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.
ESCA are the cancer types where CTBP2P9 tumor–normal differential expression is most reproducible.