CTBP2P8

Across TCGA pan-cancer cohorts, CTBP2P8 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CTBP2P8’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CTBP2P8 RNA is repressed in tumor relative to normal tissue. In most cancer types CTBP2P8 is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.

KIRC, BRCA, and LUSC are the cancer types where CTBP2P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CTBP2P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.120	.006	8	view →
BRCA	All	III,IV	−0.526	<.001	6	view →
LUSC	All	All	−0.207	<.001	6	view →
THCA	Female	All	−0.254	<.001	5	view →
LUAD	Male	III,IV	−0.273	.005	4	view →
READ	Male	All	−0.343	.015	2	view →
STAD	Male	IV	−0.339	.007	2	view →
KIRP	All	All	−0.189	.005	2	view →
KIRP	All	IV	+0.122	.015	2	view →
ESCA	Female	All	−0.683	.046	1	view →
KICH	Male	All	−0.144	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

CTBP2P8–KIRC

Open the KIRC breakdown →