Across TCGA pan-cancer cohorts, CTBP2P6 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CTBP2P6’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where CTBP2P6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CTBP2P6 is over-expressed in tumor, although a few such as READ and THCA show the opposite, repressed pattern.
BRCA, COAD, and READ are the cancer types where CTBP2P6 tumor–normal differential expression is most reproducible.