CTBP2

Across TCGA pan-cancer cohorts, CTBP2 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CTBP2 data layer compared with 25 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher CTBP2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CTBP2 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

STAD, KIRC, and SKCM are the cancer types where CTBP2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	III,IV	0.268	0.639	.002	30	view →
KIRC	OS	Median	All	0.160	0.656	.002	12	view →
SKCM	DFS	Median	III,IV	0.016	0.648	<.001	9	view →
UCEC	DFS	Median	II,III,IV	0.867	0.306	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CTBP2–STAD (OS)

Open the STAD breakdown →