CTBP2

Across TCGA patient cohorts, CTBP2 mutation is significantly associated with the RNA expression of many other genes, with 2,364 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTBP2-associated genes across cancer lineages are ZNF367, FAXDC2, and UQCRH. Each is linked with CTBP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CTBP2-to-partner and partner-to-CTBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF367 grouped by CTBP2-low versus CTBP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTBP2→partner) and Y-score (partner→CTBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF367 →	+0.504	+1.469	<.001	<.001	3	3
UCEC	FAXDC2 →	-0.495	-2.381	<.001	<.001	3	3
UCEC	UQCRH →	+0.536	+1.839	.008	.002	3	3
UCEC	RAPGEF4 →	-0.248	-1.300	.004	.002	3	3
UCEC	ATP1B2 →	-0.639	-2.989	<.001	<.001	3	3
UCEC	RNU6ATAC30P →	+0.174	+1.195	.003	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,364 associations by consensus.

ZNF367 by CTBP2 expression — UCEC

Explore this box plot interactively →