CTBP2

Across TCGA cell cohorts, CTBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,468 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CTBP2-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Viral genome replication, and Spindle localization. Each is linked with CTBP2 in more than 11 cancer types. Because this analysis shows association rather than direction, both CTBP2-to-partner and partner-to-CTBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by CTBP2-low versus CTBP2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTBP2→partner) and Y-score (partner→CTBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.107	+0.896	<.001	<.001	3	12
BREAST	Viral genome replication →	+0.172	+0.906	<.001	<.001	3	12
SOFT_TISSUE	Spindle localization →	+0.093	+0.901	.001	<.001	3	11
SOFT_TISSUE	Establishment of spindle localization →	+0.089	+0.871	.001	<.001	3	10
BONE	Regulation of translation at postsynapse, modulating synaptic transmission →	+0.116	+1.285	<.001	.002	3	10
URINARY_TRACT	CAMP/PKA signal transduction →	+0.197	+0.603	.002	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,468 associations by consensus.

Viral translational termination-reinitiation by CTBP2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →