CTBP1

Across TCGA pan-cancer cohorts, CTBP1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CTBP1 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CTBP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CTBP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and PDAC are the cancer types where CTBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	III,IV	0.853	0.316	.001	49	view →
LUAD	DFS	Median	All	0.830	0.635	.003	33	view →
PDAC	OS	Tertile	III,IV	0.857	0.379	.028	13	view →
UCEC	DFS	Quartile	III,IV	0.288	1.000	.027	8	view →
LSCC	DFS	Median	All	0.595	0.804	.007	7	view →
GBM	DFS	Quartile	All	0.938	0.705	.009	5	view →
HNSC	DFS	Quartile	III,IV	0.966	0.738	.021	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CTBP1–CCRCC (DFS)

Open the CCRCC breakdown →