CTAGE9

Across TCGA patient cohorts, CTAGE9 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTAGE9-associated genes across cancer lineages are PCNA, STAT3_pY705, and CD49b. Each is linked with CTAGE9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTAGE9-to-partner and partner-to-CTAGE9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by CTAGE9-low versus CTAGE9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTAGE9→partner) and Y-score (partner→CTAGE9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.187	+2.000	.027	.010	3	2
UCEC	STAT3_pY705 →	-0.385	-1.584	<.001	.036	3	2
UCEC	CD49b →	-0.256	-2.308	.021	.033	3	2
UCEC	Cyclin-B1 →	+0.698	+2.502	.001	.002	3	2
UCEC	EGFR →	-0.165	-2.321	.008	.034	3	1
UCEC	eIF4E →	+0.174	+2.000	.036	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

PCNA by CTAGE9 expression — UCEC

Explore this box plot interactively →