Across TCGA patient cohorts, CTAGE4 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CTAGE4-associated genes across cancer lineages are CYCSP53, NUDT4B, and DUXAP5. Each is linked with CTAGE4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTAGE4-to-partner and partner-to-CTAGE4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTAGE4→partner) and Y-score (partner→CTAGE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CYCSP53 →	+0.329	+5.771	<.001	.003	3	1
UCEC	NUDT4B →	+0.105	+5.621	<.001	.004	3	1
SKCM	DUXAP5 →	+0.180	+5.594	<.001	.004	3	1
SKCM	CYP2C60P →	+1.003	+6.469	<.001	.001	3	1
SKCM	RN7SL460P →	+0.225	+5.594	<.001	.004	3	1
SKCM	RN7SL44P →	+0.276	+5.097	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

CTAGE4 survival (RNA) · tumor vs normal (RNA) · all CTAGE4 data types